Global Distribution of wild isolates
Most research groups that study C. elegans focus on the laboratory-adapted strain (called N2) isolated in
Bristol, England in the 1950s. We have learned a great deal about basic biological processes from studies of this one strain.
However, this species is found worldwide, and wild strains are as different from one another as humans are different from one another.
These strains are isolated from a variety of environments in nature when researchers collect rotting materials, including fruits,
flowers, nuts, berries, stems, leaves, and compost. We can use the natural diversity of these strains to learn about how populations
of individuals are genetically different from another and how those differences might impact disease.